肿瘤到肿瘤转移：透明细胞肾细胞癌转移至肺腺癌的罕见病例
Tumor-to-tumor metastasis: a rare case of clear cell renal cell carcinoma metastasizing into lung adenocarcinoma.
作者
作者单位
- Department of General and Specialized Surgery and Anesthesiology, University of Rome Sapienza.
- Department of Radiological, Oncological and Pathological Sciences, University of Rome Sapienza.
摘要
中文
肿瘤到肿瘤转移（TTM）是一种非常罕见的情况，即恶性肿瘤（供体）转移至另一个原发肿瘤（受体），良性或恶性。我们报告一例74岁男性，曾因透明细胞肾细胞癌（ccRCC）接受手术治疗，在四年随访CT扫描中发现右肺上叶新发亚实性结节。患者接受右单孔胸腔镜S1段切除术和纵隔淋巴结清扫。组织病理学检查显示肺腺癌（LUAD）内含转移性ccRCC病灶，无淋巴结受累或其他转移证据。目前患者无病生存。肾肿瘤细胞转移至原发肺肿瘤极为罕见。据我们所知，这是首例ccRCC转移至LUAD而无系统性播散证据的报道。
English
Tumor-to-tumor metastasis (TTM) is a very rare condition in which a malignant tumor (donor) metastasizes into another primary neoplasm, either benign or malignant (recipient). We report the case of a 74-year-old man previously surgically treated for a clear cell renal cell carcinoma(ccRCC) who developped a new subsolid nodule in the right upper pulmonary lobe discovered at a four-year follow-up CT scan. The patient underwent a right uniportal thoracoscopic S1 segmentectomy and mediastinal lymph node dissection. Histopathological examination revealed a lung adenocarcinoma (LUAD) containing a focus of metastatic ccRCC without lymph node involvement or evidence of additional metastatic disease. To date, the patient remains disease-free. Metastasis of renal tumor cells into a primary lung tumor is exceptionally rare. To our knowledge, this is the first reported case of ccRCC metastasizing into LUAD without evidence of systemic dissemination.
分类与指标
- 研究类型
- 临床研究
- 病种
- 肺癌
- JCR 分区
- Q3
- 影响因子
- 1.4
- 新锐分区
- 3区